APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
5 - 10 μg/ml |
Not tested in other applications.
Calculated MW
Predict Reactivity
Hamster, Pig, Elephant, Ferret, Gibbon, Gorilla, Horse, Marmoset, Panda(>80% identity)
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
0.1% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Synthetic 17 amino acid peptide from C-terminus of human DRD4 / Dopamine Receptor D4.
Purification
Purified by affinity chromatography
Conjugation
Unconjugated
RRID
AB_375952
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
dopamine receptor D4 , D4DR , DRD4 , Dopamine receptor D4
Cellular Localization
Cell membrane
Background
This gene encodes the D4 subtype of the dopamine receptor. The D4 subtype is a G-protein coupled receptor which inhibits adenylyl cyclase. It is a target for drugs which treat schizophrenia and Parkinson disease. Mutations in this gene have been associated with various behavioral phenotypes, including autonomic nervous system dysfunction, attention deficit/hyperactivity disorder, and the personality trait of novelty seeking. This gene contains a polymorphic number (2-10 copies) of tandem 48 nt repeats; the sequence shown contains four repeats. [provided by RefSeq, Jul 2008]
Database
Research Area
DATA IMAGES
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GTX71827 IHC-P Image
IHC-P analysis of brain, hippocampus, dentate gyrus tissue using GTX71827 Dopamine Receptor D4 antibody.
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GTX71827 IHC-P Image
IHC-P analysis of human brain, glioblastoma tissue using GTX71827 Dopamine Receptor D4 antibody. Antigen retrieval : Heat-induced antigen retrieval
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GTX71827 IHC-P Image
IHC-P analysis of human ovary, carcinoma tissue using GTX71827 Dopamine Receptor D4 antibody. Antigen retrieval : Heat-induced antigen retrieval
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GTX71827 IHC-P Image
IHC-P analysis of human brain, neurons and glia tissue using GTX71827 Dopamine Receptor D4 antibody. Antigen retrieval : Heat-induced antigen retrieval
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GTX71827 IHC-P Image
IHC-P analysis of human lung, small cell carcinoma tissue using GTX71827 Dopamine Receptor D4 antibody. Antigen retrieval : Heat-induced antigen retrieval
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REFERENCE
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REVIEW
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