GeneTex
United States (US)

Dopamine Transporter antibody

Cat No. GTX30992

Host Rat
Clonality Monoclonal
Clone Name DAT-Nt(4F8)
Isotype IgG2a
Application WB, IHC-Fr
Reactivity Human, Mouse, Rat, Monkey
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB Assay dependent
IHC-Fr 1/1000-1/10,000

Note :

WB
This antibody recognizes a diffuse band at approximatley 70-85 kDa on extracts from human caudate, putamen and nucleus accumbens..

Not tested in other applications.

Calculated MW

68 kDa. ( Note )

Specificity/Sensitivity

GTX30992 is specific for the dopamine transporter, N-terminus. It does not cross react with serotonin and norepinephrine transporters.
PROPERTIES

Form

Liquid

Buffer

Tissue Culture Supernatant

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

N-terminus of human dopamine transporter fused to Glutathione S-transferase.

Purification

Tissue Culture Supernatant

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Solute Carrier Family 6 Member 3,Dat,Dat1,Pkdys,Pkdys1,Slc6A3

Background

This gene encodes a dopamine transporter which is a member of the sodium- and chloride-dependent neurotransmitter transporter family. The 3' UTR of this gene contains a 40 bp tandem repeat, referred to as a variable number tandem repeat or VNTR, which can be present in 3 to 11 copies. Variation in the number of repeats is associated with idiopathic epilepsy, attention-deficit hyperactivity disorder, dependence on alcohol and cocaine, susceptibility to Parkinson disease and protection against nicotine dependence.[provided by RefSeq, Nov 2009]

Database

Research Area

Package List Price ($)
$ 339