APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
1 - 2 μg/mL |
Assay dependent |
Assay dependent |
Not tested in other applications.
Calculated MW
Positive Control
SK-N-SH Cell Lysate(GTX23956)
Product Note
At least two isoforms of ERAP1 are known to exist; this antibody will detect both isoforms. ERAP1 antibody is predicted to not cross-react with ERAP2.
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
0.02% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
ERAP1 antibody was raised against a 19 amino acid peptide near the carboxy terminus of human ERAP.The immunogen is located within amino acids 730 - 780 of ERAP1 .
Purification
Purified by antigen-affinity chromatography
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
endoplasmic reticulum aminopeptidase 1 , A-LAP , ALAP , APPILS , ARTS-1 , ARTS1 , ERAAP , ERAAP1 , PILS-AP , PILSAP
Cellular Localization
Endoplasmic reticulum membrane
Background
The protein encoded by this gene is an aminopeptidase involved in trimming HLA class I-binding precursors so that they can be presented on MHC class I molecules. The encoded protein acts as a monomer or as a heterodimer with ERAP2. This protein may also be involved in blood pressure regulation by inactivation of angiotensin II. Three transcript variants encoding two different isoforms have been found for this gene.[provided by RefSeq, Oct 2010]
Database
Research Area
DATA IMAGES
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GTX31553 IHC-P Image
IHC-P analysis of mouse brain tissue using GTX31553 ERAP1 antibody. Working concentration : 20 μg/ml
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GTX31553 IHC-P Image
IHC-P analysis of mouse brain tissue using GTX31553 ERAP1 antibody. Working concentration : 5 μg/ml
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GTX31553 WB Image
WB analysis of SK-N-SH cell lysate using GTX31553 ERAP1 antibody. Working concentration : (A) 1 and (B) 2 μg/ml
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REFERENCE
There are currently no references for ERAP1 antibody (GTX31553). Be the first to share your publications with this product.
REVIEW
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