APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
1:500-1:1000 |
1:50-1:200 |
Not tested in other applications.
Calculated MW
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
15mM Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Synthetic peptide, corresponding to amino acids 435-489 of Human ERAP1.
Purification
Purified by antigen-affinity chromatography
From serum
Purity
> 95% (by SDS-PAGE)
Conjugation
Unconjugated
Note
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET
Synonyms
endoplasmic reticulum aminopeptidase 1 , A-LAP , ALAP , APPILS , ARTS-1 , ARTS1 , ERAAP , ERAAP1 , PILS-AP , PILSAP
Cellular Localization
Endoplasmic reticulum membrane
Background
The protein encoded by this gene is an aminopeptidase involved in trimming HLA class I-binding precursors so that they can be presented on MHC class I molecules. The encoded protein acts as a monomer or as a heterodimer with ERAP2. This protein may also be involved in blood pressure regulation by inactivation of angiotensin II. Three transcript variants encoding two different isoforms have been found for this gene.[provided by RefSeq, Oct 2010]
Database
Research Area
DATA IMAGES
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GTX66660 WB Image
WB analysis of various samples using GTX66660 ERAP1 antibody. Lane1 : HepG2 whole cell lysate(40ug) Lane2 : HEK293T whole cell lysate(20ug) Lane3 : PC12 whole cell lysate(20ug) Lane4 : AML-12 whole cell lysate(40ug) Dilution : 1:500
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GTX66660 IHC-P Image
IHC-P analysis of human breast carcinoma tissue using GTX66660 ERAP1 antibody. Dilution : 1:100
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REFERENCE
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REVIEW
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