APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| Assay dependent |
| Assay dependent |
| 4 - 11 μg/ml |
Not tested in other applications.
Calculated MW
Predict Reactivity
Monkey, Gibbon, Gorilla, Marmoset(>80% identity)
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
0.1% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Synthetic 19 amino acid peptide from N-terminal extracellular domain of human EDNRB.
Purification
Purified by affinity chromatography
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
endothelin receptor type B , ABCDS , EDNRB , ETB , ETB1 , ETBR , ETRB , HSCR , HSCR2 , WS4A , Endothelin B Receptor
Cellular Localization
Cell membrane
Background
The protein encoded by this gene is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene. Alternative splicing and the use of alternative promoters results in multiple transcript variants. [provided by RefSeq, Oct 2016]
Database
Research Area
DATA IMAGES
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GTX12980 IHC-P Image
IHC-P analysis of brain, alzheimer's senile plaque tissue using GTX12980 Endothelin B Receptor antibody.
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GTX12980 IHC-P Image
IHC-P analysis of human adrenal, medulla tissue using GTX12980 Endothelin B Receptor antibody.
Antigen retrieval : Heat-induced antigen retrieval
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GTX12980 IHC-P Image
IHC-P analysis of human colon, carcinoma tissue using GTX12980 Endothelin B Receptor antibody.
Antigen retrieval : Heat-induced antigen retrieval
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GTX12980 IHC-P Image
IHC-P analysis of human lung, small cell carcinoma tissue using GTX12980 Endothelin B Receptor antibody.
Antigen retrieval : Heat-induced antigen retrieval
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GTX12980 ICC/IF Image
ICC/IF analysis of HEK293 transfected with Endothelin B Receptor using GTX12980 Endothelin B Receptor antibody.
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GTX12980 IHC-P Image
IHC-P analysis of brain, dementia, senile plaque tissue using GTX12980 Endothelin B Receptor antibody.
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GTX12980 IHC-P Image
IHC-P analysis of artery, smooth muscle tissue using GTX12980 Endothelin B Receptor antibody.
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REFERENCE
There are currently no references for Endothelin B Receptor antibody (GTX12980). Be the first to share your publications with this product.
REVIEW
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