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Ezrin antibody [3C12]

Anti-Ezrin antibody [3C12] used in IHC (Paraffin sections) (IHC-P). GTX24069

Cat. No. GTX24069

Reference 1

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 3C12

Isotype

 IgG1

Application

 IHC-P, IHC

Reactivity

 Human, Mouse
Package
500 μl ($449)
See all Ezrin products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1:50‐1:100
IHC Assay dependent

Note :

IHC-P
Recommendations for antigen retrieval : Citrate Buffer pH 6.0 at room temperature for 30 mins.
Not tested in other applications.

Calculated MW

69 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

BALB/C mice were immunized with a recombinant fragment of human ezrin corresponding to amino acid 362-585.

Purification

Purified IgG

Conjugation

Unconjugated

RRID

AB_369882

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

ezrin , CVIL , CVL , HEL-S-105 , VIL2

Cellular Localization

Apical cell membrane , Cytoplasm, cytoskeleton

Background

The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described for this gene. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-Ezrin antibody [3C12] used in IHC (Paraffin sections) (IHC-P). GTX24069

GTX24069 IHC-P Image

IHC-P analysis of human lung tissue using GTX24069 Ezrin antibody [3C12].

REFERENCE

Application Reference

Munch J et al. J Biol Chem 2018; (Epub) Ca2+-activated Cl- currents in the murine vomeronasal organ enhance neuronal spiking but are dispensable for male-male aggression.
Application : IHC
Reactivity : Mouse
Submit a Reference

REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 449