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FBXL17 antibody [C1C3]

Anti-FBXL17 antibody [C1C3] used in IHC (Paraffin sections) (IHC-P). GTX119211
Anti-FBXL17 antibody [C1C3] used in IHC (Paraffin sections) (IHC-P). GTX119211
Anti-FBXL17 antibody [C1C3] used in IHC (Paraffin sections) (IHC-P). GTX119211
Anti-FBXL17 antibody [C1C3] used in Western Blot (WB). GTX119211

Cat. No. GTX119211

Reference 1

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human, Mouse
Package
100 μl ($399),
25 μl ($169)
See all FBXL17 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500-1:3000
IHC-P 1:100-1:1000
Not tested in other applications.

Calculated MW

76 kDa. ( Note )

Positive Control

MCF-7

Predict Reactivity

Rat(>80% identity)

PROPERTIES

Form

Liquid

Buffer

PBS, 20% Glycerol

Preservative

0.025% ProClin 300

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.76 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant protein encompassing a sequence within the center region of human FBXL17. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

RRID

AB_10618294

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

F-box and leucine rich repeat protein 17 , FBXO13 , Fbl17 , Fbx13

Background

Members of the F-box protein family, such as FBXL17, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM]

Database

Research Area

DATA IMAGES

Anti-FBXL17 antibody [C1C3] used in IHC (Paraffin sections) (IHC-P). GTX119211

GTX119211 IHC-P Image

FBXL17 antibody [C1C3] detects FBXL17 protein at cytoplasm and nucleus by immunohistochemical analysis.
Sample: Paraffin-embedded mouse heart.
FBXL17 stained by FBXL17 antibody [C1C3] (GTX119211) diluted at 1:500.
Antigen Retrieval: Citrate buffer, pH 6.0, 15 min

Anti-FBXL17 antibody [C1C3] used in IHC (Paraffin sections) (IHC-P). GTX119211

GTX119211 IHC-P Image

FBXL17 antibody [C1C3] detects FBXL17 protein at cytoplasm and nucleus by immunohistochemical analysis.
Sample: Paraffin-embedded mouse muscle.
FBXL17 stained by FBXL17 antibody [C1C3] (GTX119211) diluted at 1:500.
Antigen Retrieval: Citrate buffer, pH 6.0, 15 min

Anti-FBXL17 antibody [C1C3] used in IHC (Paraffin sections) (IHC-P). GTX119211

GTX119211 IHC-P Image

FBXL17 antibody [C1C3] detects FBXL17 protein at cytoplasm in mouse testis by immunohistochemical analysis.
Sample: Paraffin-embedded mouse testis.
FBXL17 antibody [C1C3] (GTX119211) diluted at 1:500.

Antigen Retrieval: Citrate buffer, pH 6.0, 15 min

Anti-FBXL17 antibody [C1C3] used in Western Blot (WB). GTX119211

GTX119211 WB Image

Various whole cell extracts (30 μg) were separated by 10% SDS-PAGE, and the membrane was blotted with FBXL17 antibody [C1C3] (GTX119211) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

REFERENCE

Application Reference

Mason B et al. Cell Mol Life Sci 2019; Fbxl17 is rearranged in breast cancer and loss of its activity leads to increased global O-GlcNAcylation.
Application : WB
Reactivity : Human
Submit a Reference

REVIEW

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SDS
Glycerol.pdf
Thimerosal.pdf
Package List Price ($)
$ 399
$ 169