APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
1:200-1:1000 |
1:10000-1:100000 |
Assay dependent |
Not tested in other applications.
Calculated MW
Predict Reactivity
Bovine, Dog, Chicken, Monkey, Horse(>80% identity)
PROPERTIES
Form
Liquid
Buffer
0.02M Potassium Phosphate, 0.15M NaCl
Preservative
0.01% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
0.8 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
A synthetic peptide corresponding to a region near the N-terminal of human βTrCP2 protein.
Purification
Purified by affinity chromatography
From serum
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
F-box and WD repeat domain containing 11 , BTRC2 , BTRCP2 , FBW1B , FBXW1B , Fbw11 , Hos
Cellular Localization
Cytoplasm,Nucleus
Background
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbws class and, in addition to an F-box, contains multiple WD40 repeats. This gene contains at least 14 exons, and its alternative splicing generates 3 transcript variants diverging at the presence/absence of two alternate exons. [provided by RefSeq, Jul 2008]
Database
Research Area
DATA IMAGES
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GTX18150 WB Image
WB analysis of NIH3T3 (lane 1) and 293 (lane 2) cell lysates using GTX18150 FBXW11 antibody. Dilution : 1:200
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REFERENCE
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REVIEW
There are currently no reviews for FBXW11 antibody (GTX18150). Be the first to share your experience with this product.