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Fibrillarin antibody [38F3]

Anti-Fibrillarin antibody [38F3] used in Western Blot (WB). GTX82695

Cat. No. GTX82695

Reference 4

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 38F3

Isotype

 IgG1

Application

 WB, IHC

Reactivity

 Human, Rat
Package
100 μl ($439)
See all Fibrillarin products

APPLICATION

Application Note

Optimal working dilutions should be determined experimentally by the end user.

Calculated MW

34 kDa. ( Note )

PROPERTIES

Form

Liquid

Preservative

10mM Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Yeast

Immunogen

Yeast nuclear preparations

Purification

Total IgG fraction

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Cellular Localization

Nucleus, nucleolus

Database

Research Area

DATA IMAGES

Anti-Fibrillarin antibody [38F3] used in Western Blot (WB). GTX82695

GTX82695 WB Image

Western bot of HeLa lysate showing specific immunolabeling of the ~34k Fibrillarin protein using Fibrillarin antibody [38F3] (GTX82695).

REFERENCE

Clone Reference

Bennett CL et al. Heliyon 2020; 6 (6):e04165 Tight expression regulation of senataxin, linked to motor neuron disease and ataxia, is required to avert cell-cycle block and nucleolus disassembly.
Xiangduo Kong et al. bioRxiv 2019; (Epub) The cohesin loader NIPBL interacts with pre-ribosomal RNA and treacle to regulate ribosomal RNA synthesis.
Behm M et al. J Cell Sci 2017; 130 (4):745-753 Accumulation of nuclear ADAR2 regulates adenosine-to-inosine RNA editing during neuronal development.
Zougman A et al. Nucleic Acids Res 2011; 39 (16):7103-13 Identification and characterization of a novel ubiquitous nucleolar protein 'NARR' encoded by a gene overlapping the rab34 oncogene.
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Package List Price ($)
$ 439