GeneTex

  • Country / Location Selection

United States (US)

Fibrillin 1 antibody [11C1.3]

Cat. No. GTX23090

Reference 4

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 11C1.3

Isotype

 IgG1

Application

 WB, ICC/IF, IHC-P, IHC-Fr, EM

Reactivity

 Human, Mouse, Bovine
Package
500 μl ($399)
See all Fibrillin 1 products

APPLICATION

Application Note

Electron Microscopy / Immunofluorescence / Immunohistochemistry: assay dependent. Western blot: use at a concentration of 1 - 2μg/ml for 2 hours at RT. By Western blot this detects a band of ~ 350 kDa, which corresponds to the predicted molecular weight of Fibrillin 1. Optimal dilutions/concentrations should be determined by the end user.

Calculated MW

312 kDa. ( Note )

Positive Control

Normal skin fibroblasts

PROPERTIES

Form

Liquid

Buffer

10mM PBS, 0.2% BSA

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Concentration

0.2 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Bovine

Immunogen

Microfibrils from zonular apparatus of bovine eye.

Purification

Protein G purified

Conjugation

Unconjugated

RRID

AB_384938

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

fibrillin 1

Cellular Localization

Secreted

Database

Research Area

REFERENCE

Application Reference

Alicia De Maria et al. Invest Ophthalmol Vis Sci 2021; 62 (15) : 27 Compositional Analysis of Extracellular Aggregates in the Eyes of Patients With Exfoliation Syndrome and Exfoliation Glaucoma.
Reactivity : Human
Chen C et al. J Exp Med 2015; 212 (1) : 73-91 mTOR inhibition rescues osteopenia in mice with systemic sclerosis.
Application : WB
Reactivity : Mouse
Xu H et al. Am J Physiol Cell Physiol 2011; 300 (3) : C550-6 Abnormal fibrillin-1 expression and chronic oxidative stress mediate endothelial mesenchymal transition in a murine model of systemic sclerosis.
Application : WB
Reactivity : Mouse

Clone Reference

Shan Shan Qiu et al. PLoS One 2015; 10 (12) Effect of P144® (Anti-TGF-β) in an "In Vivo" Human Hypertrophic Scar Model in Nude Mice
Application : IHC-P
Reactivity : Mouse
Submit a Reference

REVIEW

There are currently no reviews for Fibrillin 1 antibody [11C1.3] (GTX23090). Be the first to share your experience with this product.
Submit a Review
SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399