GeneTex
United States (US)

GDF5 recombinant protein

Cat No. GTX65287

Application ELISA, Functional Assay, Apuri, Blocking
Reactivity Human
Species Human
APPLICATION

Application Note

The ED50 as determined by its ability to induce alkaline phosphatase production by ATDC-5 chondrogenic cells is 1-2 ug/ml.

Calculated MW

27 kDa. ( Note )
PROPERTIES

Form

Lyophilized powder

Buffer

Sterile filtered and lyophilized from 10 mM Sodium Citrate, pH 3.5.

Storage

Store at -20 ºC. Stable for 12 months from date of receipt.Reconstitute to a concentration of 0.1-1.0 mg/ml in water containing BSA (50 mg BSA per 1 mg of protein). This solution can then be diluted into other aqueous buffers.

Antigen Species

Human

Expression System

E. coli

Purification


Purity was assessed by SDS-PAGE (≥98%) and by HPLC (≥98%).

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

GDF5, Growth differentiation factor 5, CDMP1, Radotermin, Growth differentiation factor5, Cartilage-derived morphogenetic protein-1, LAP4, CDMP-1, Cartilagederived morphogenetic protein1, GDF-5, BMP-14, BMP14, SYNS2, GDF 5, CDMP 1, BMP 14

Background

BMPs (bone morphogenetic proteins) belong to the TGF-beta superfamily of structurally related signaling proteins. As implied by their name, BMPs promote and regulate bone development, growth, remodeling and repair, in both prenatal development and postnatal growth of eye, heart, kidney, skin, and other tissues. In addition to its osteogenic activity, BMP-14 is a principal inhibitor of cartilage development and is predominantly expressed in long bone during human embryonic development. Recombinant human BMP-14 is a 27 kDa homodimeric protein consisting of two 120 amino acid polypeptide chains.
Package List Price ($)
$ 199