GeneTex
United States (US)

GDF7 recombinant protein

Cat No. GTX65463

Application ELISA, Functional Assay, Apuri, Blocking
Reactivity Human
Species Human
APPLICATION

Application Note

The protein is biologically active as determined by its ability to induce alkaline phosphatase production by ADTC5 mouse chondrogenic cells. The ED50 for this effect is typically 0.2 – 2.5 ug/ml.

Calculated MW

27 kDa. ( Note )
PROPERTIES

Form

Lyophilized powder

Buffer

Sterile filtered and lyophilized with no additives

Storage

Reconstitute to a concentration of 0.1-1.0 mg/ml in water containing BSA (50 mg BSA per 1 mg of protein). This solution can then be diluted into other aqueous buffers. Store at -20 ºC. Stable for 12 months from date of receipt.

Antigen Species

Human

Expression System

E. coli

Purification


Purity was assessed by SDS-PAGE (≥98%) and by HPLC (≥98%).

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Growth Differentiation Factor 7,Bmp12,Gdf7

Background

BMPs (bone morphogenetic proteins) belong to the TGF-beta superfamily of structurally related signaling proteins. As implied by their name, BMPs promote and regulate bone development, growth, remodeling and repair, in both prenatal development and postnatal growth of eye, heart, kidney, skin, and other tissues. BMP-12 is highly conserved across species. BMP-12 regulates chondrogenesis, bone morphogenesis, and neuron differentiation. Recombinant human BMP-12 is a 27 kDa disulfide-linked homodimer containing two 122 amino acid polypeptide chains.

Research Area

Package List Price ($)
$ 259