Sterile filtered and lyophilized with no additives
Reconstitute to a concentration of 0.1-1.0 mg/ml in water containing BSA (50 mg BSA per 1 mg of protein). This solution can then be diluted into other aqueous buffers. Store at -20 ºC. Stable for 12 months from date of receipt.
Purity was assessed by SDS-PAGE (≥98%) and by HPLC (≥98%).
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Growth Differentiation Factor 7,Bmp12,Gdf7
BMPs (bone morphogenetic proteins) belong to the TGF-beta superfamily of structurally related signaling proteins. As implied by their name, BMPs promote and regulate bone development, growth, remodeling and repair, in both prenatal development and postnatal growth of eye, heart, kidney, skin, and other tissues. BMP-12 is highly conserved across species. BMP-12 regulates chondrogenesis, bone morphogenesis, and neuron differentiation. Recombinant human BMP-12 is a 27 kDa disulfide-linked homodimer containing two 122 amino acid polypeptide chains.