GeneTex
United States (US)

GDNF recombinant protein

Cat No. GTX65105

Application ELISA, Functional Assay, Apuri, Blocking
Reactivity Human
Species Human
APPLICATION

Application Note

The ED50 as determined by the dose-dependent dopamine uptake by rat ventral mesencephalic cultures was found to be in the range of 4-8 ng/ml.

Calculated MW

30.1 kDa. ( Note )
PROPERTIES

Form

Lyophilized powder

Buffer

10 mM Sodium Citrate + 150 mM NaCl, pH 4.0.

Storage

Reconstitute in water to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers and stored at 4ºC for 1 week or –20ºC for future use.

Antigen Species

Human

Expression System

E. coli

Purification


Purity was assessed by SDS-PAGE (≥98%) and by HPLC (≥98%).

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

ATF1, GlialDerived Neurotrophic Factor, GDNF, Glial-Derived Neurotrophic Factor, ATF-1, ATF 1

Background

Human GDNF (Glial-Derived Neurotrophic Factor) is a 30.1 kDa protein that specifically promotes dopamine uptake and survival of midbrain neurons. GDNF is a disslphide-linked homodimer, formed by two identical 134 amino acids subunits.

Research Area

Package List Price ($)
$ 249