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GJB1 antibody [GJB1/1753]

Anti-GJB1 antibody [GJB1/1753] used in IHC (Paraffin sections) (IHC-P). GTX34760
Anti-GJB1 antibody [GJB1/1753] used in IHC (Paraffin sections) (IHC-P). GTX34760

Cat. No. GTX34760

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 GJB1/1753

Isotype

 IgG

Application

 IHC-P

Reactivity

 Human, Mouse, Rat
Package
100 μg ($529)
See all GJB1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 0.1-0.2μg/ml for 30 min at RT

Note :

IHC-P
Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95ºC followed by cooling at RT for 20 minutes.
Not tested in other applications.

Calculated MW

32 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

10mM PBS, 0.05% BSA

Preservative

0.05% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.2 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant human GJB1 protein

Purification

Protein G purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

CMTX , CMTX1 , CX32 , GJB1 , gap junction protein beta 1 , Connexin 32

Cellular Localization

Cell membrane,Cell junction,Gap junction

Background

This gene encodes a member of the gap junction protein family. The gap junction proteins are membrane-spanning proteins that assemble to form gap junction channels that facilitate the transfer of ions and small molecules between cells. According to sequence similarities at the nucleotide and amino acid levels, the gap junction proteins are divided into two categories, alpha and beta. Mutations in this gene cause X-linked Charcot-Marie-Tooth disease, an inherited peripheral neuropathy. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Oct 2008]

Database

Research Area

DATA IMAGES

Anti-GJB1 antibody [GJB1/1753] used in IHC (Paraffin sections) (IHC-P). GTX34760

GTX34760 IHC-P Image

IHC-P analysis of human liver tissue using GTX34760 GJB1 antibody [GJB1/1753].

Anti-GJB1 antibody [GJB1/1753] used in IHC (Paraffin sections) (IHC-P). GTX34760

GTX34760 IHC-P Image

IHC-P analysis of human tonsil tissue using GTX34760 GJB1 antibody [GJB1/1753].

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 529