APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
Assay dependent |
Not tested in other applications.
Calculated MW
Product Note
This antibody binds human ghrelin.
PROPERTIES
Form
Liquid
Buffer
0.01M Phosphate buffer pH7.4, 0.14M NaCl
Preservative
No preservative
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Immunogen
Synthetic ghrelin (14-28)
Purification
Biotinylated
Conjugation
Biotin
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
ghrelin and obestatin prepropeptide , MTLRP
Cellular Localization
Secreted
Background
This gene encodes the ghrelin-obestatin preproprotein that is cleaved to yield two peptides, ghrelin and obestatin. Ghrelin is a powerful appetite stimulant and plays an important role in energy homeostasis. Its secretion is initiated when the stomach is empty, whereupon it binds to the growth hormone secretagogue receptor in the hypothalamus which results in the secretion of growth hormone (somatotropin). Ghrelin is thought to regulate multiple activities, including hunger, reward perception via the mesolimbic pathway, gastric acid secretion, gastrointestinal motility, and pancreatic glucose-stimulated insulin secretion. It was initially proposed that obestatin plays an opposing role to ghrelin by promoting satiety and thus decreasing food intake, but this action is still debated. Recent reports suggest multiple metabolic roles for obestatin, including regulating adipocyte function and glucose metabolism. Alternative splicing results in multiple transcript variants. In addition, antisense transcripts for this gene have been identified and may potentially regulate ghrelin-obestatin preproprotein expression. [provided by RefSeq, Nov 2014]
Database
Research Area
DATA IMAGES
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GTX60947-02 ELISA Image
The calibration curve of a sandwich assay for Ghrelin using GTX60946 as the capture antibody and GTX60947- 02 as the biotinylated detection antibody.
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REFERENCE
There are currently no references for Ghrelin antibody [121] (Biotin) (GTX60947-02). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for Ghrelin antibody [121] (Biotin) (GTX60947-02). Be the first to share your experience with this product.