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H-Ras antibody [H-RAS-03]

Anti-H-Ras antibody [H-RAS-03] used in Western Blot (WB). GTX80140

Cat. No. GTX80140

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 H-RAS-03

Isotype

 IgG1

Application

 WB

Reactivity

 Human
Package
100 μg ($399)
See all H-Ras products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB Assay dependent
Not tested in other applications.

Calculated MW

21 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

15mM Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Peptide corresponding to amino acids DIHQYREQIKRVKDSDDC of human H-Ras protein

Purification

Protein A purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

CBAS/HAS , CHARAS1 , CHRAS , CTLO , HAMSV , HRAS , HRAS1 , HRASIDX , HRas protooncogene, GTPase , RASH1 , p21ras , H-Ras , HRas proto-oncogene, GTPase

Cellular Localization

Cell membrane,Golgi apparatus,Golgi apparatus membrane,Nucleus,Cytoplasm,Perinuclear region

Background

This gene belongs to the Ras oncogene family, whose members are related to the transforming genes of mammalian sarcoma retroviruses. The products encoded by these genes function in signal transduction pathways. These proteins can bind GTP and GDP, and they have intrinsic GTPase activity. This protein undergoes a continuous cycle of de- and re-palmitoylation, which regulates its rapid exchange between the plasma membrane and the Golgi apparatus. Mutations in this gene cause Costello syndrome, a disease characterized by increased growth at the prenatal stage, growth deficiency at the postnatal stage, predisposition to tumor formation, cognitive disability, skin and musculoskeletal abnormalities, distinctive facial appearance and cardiovascular abnormalities. Defects in this gene are implicated in a variety of cancers, including bladder cancer, follicular thyroid cancer, and oral squamous cell carcinoma. Multiple transcript variants, which encode different isoforms, have been identified for this gene. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-H-Ras antibody [H-RAS-03] used in Western Blot (WB). GTX80140

GTX80140 WB Image

WB analysis of various samples using GTX80140 H-Ras antibody [H-RAS-03].
Lane 1 : HeLa
Lane 2 : K567
Lane 3 : Raji

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399