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HLA-E antibody [MEM-E/02]

Anti-HLA-E antibody [MEM-E/02] used in Western Blot (WB). GTX75948

Cat. No. GTX75948

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 MEM-E/02

Isotype

 IgG1

Application

 WB

Reactivity

 Human
Package
200 μg ($549)
See all HLA-E products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB Assay dependent
Not tested in other applications.

Calculated MW

40 kDa. ( Note )

Product Note

This antibody reacts with the denatured heavy chain of the non-classical MHC class I HLA-E and does not cross react with HLA-A, -B, -C or G.

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1.0 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant HLA-E.

Purification

Protein A purified

Conjugation

Unconjugated

RRID

AB_377129

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

major histocompatibility complex, class I, E , HLA-6.2 , QA1

Cellular Localization

Cell membrane , Golgi apparatus membrane

Background

HLA-E belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-E binds a restricted subset of peptides derived from the leader peptides of other class I molecules. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-HLA-E antibody [MEM-E/02] used in Western Blot (WB). GTX75948

GTX75948 WB Image

WB analysis of A431 cell lysate using GTX75948 HLA-E antibody [MEM-E/02].

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 549