GeneTex
United States (US)

Heparanase 1 antibody [N1N2], N-term

Cat No. GTX100694

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application ELISA-Ag
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
ELISA-Ag Assay dependent
Not tested in other applications.

Calculated MW

61 kDa. ( Note )

Positive Control

Synthetic peptide: 1:8,000

Predict Reactivity

Human(>80% identity)
PROPERTIES

Form

Liquid

Buffer

0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human Heparanase 1. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Heparanase,Hpa,Hpa1,Hpr1,Hpse1,Hse1,Hpse

Cellular Localization

Lysosome membrane; Peripheral membrane protein , Secreted

Background

Heparan sulfate proteoglycans (HSPGs) are major components of the basement membrane and extracellular matrix. Heparanases, like HSPE, are endoglycosidases that cleave the heparan sulfate side chain of HSPGs to permit the remodeling of the extracellular matrix for cell movement or the release of bioactive molecules from the extracellular matrix or cell surface (summary by McKenzie et al., 2000 [PubMed 11027606]).[supplied by OMIM]

Database

Research Area

SDS
Glycerol.pdf
Thimerosal.pdf
Package List Price ($)
$ 319
$ 169