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HtrA1 antibody

Anti-HtrA1 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX53558
Anti-HtrA1 antibody used in Western Blot (WB). GTX53558
Anti-HtrA1 antibody used in IHC (Paraffin sections) (IHC-P). GTX53558

Cat. No. GTX53558

Reference 1

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, IHC-P

Reactivity

 Human, Mouse
Package
200 μl ($399)
See all HTRA1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:2000
ICC/IF 1:10-1:50
IHC-P 1:10-1:50
Not tested in other applications.

Calculated MW

51 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

KLH conjugated synthetic peptide between 116-147 amino acids from the N-terminal region of human HtrA1.

Purification

Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

HtrA serine peptidase 1 , ARMD7 , CADASIL2 , CARASIL , HtrA , L56 , ORF480 , PRSS11

Cellular Localization

Cell membrane,Secreted,Cytoplasm, cytosol

Background

This gene encodes a member of the trypsin family of serine proteases. This protein is a secreted enzyme that is proposed to regulate the availability of insulin-like growth factors (IGFs) by cleaving IGF-binding proteins. It has also been suggested to be a regulator of cell growth. Variations in the promoter region of this gene are the cause of susceptibility to age-related macular degeneration type 7. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-HtrA1 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX53558

GTX53558 ICC/IF Image

ICC/IF analysis of HeLa cells using GTX53558 HtrA1 antibody.
Green : HtrA1
Blue : DAPI

Anti-HtrA1 antibody used in Western Blot (WB). GTX53558

GTX53558 WB Image

WB analysis of mouse brain lysate using GTX53558 HtrA1 antibody.
Loading : 20 μg per lane
Dilution : 1:2000

Anti-HtrA1 antibody used in IHC (Paraffin sections) (IHC-P). GTX53558

GTX53558 IHC-P Image

IHC-P analysis of human kidney tissue using GTX53558 HtrA1 antibody.

REFERENCE

Application Reference

Kanoko Yoshida et al. Int J Mol Sci 2021; 22 (7) Alpha-1 Antitrypsin-Induced Endoplasmic Reticulum Stress Promotes Invasion by Extravillous Trophoblasts.
Application : IHC-P
Reactivity : Human
Submit a Reference

REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399