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Human RGS17 protein, His tag

Human RGS17 protein, His tag. GTX68384-pro

Cat. No. GTX68384-pro

Species

 Human
Package
100 μg ($289)
See all RGS17 protein products

APPLICATION

Observed MW

24 kDa.

PROPERTIES

Form

Liquid

Buffer

20mM Tris-HCl buffer (pH8.0), 10% Glycerol, 0.1M NaCl, 1mM DTT

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Region/Sequence

Full length protein, N-terminal His-Tag; MGSSHHHHHH SSGLVPRGSH MRKRQQSQNE GTPAVSQAPG NQRPNNTCCF CWCCCCSCSC LTVRNEERGE NAGRPTHTTK MESIQVLEEC QNPTAEEVLS WSQNFDKMMK APAGRNLFRE FLRTEYSEEN LLFWLACEDL KKEQNKKVIE EKARMIYEDY ISILSPKEVS LDSRVREVIN RNLLDPNPHM YEDAQLQIYT LMHRDSFPRF LNSQIYKSFV ESTAGSSSES

Expression System

E. coli

Purity

> 90% by SDS-PAGE.

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

regulator of G protein signaling 17 , RGS-17 , RGSZ2 , hRGS17

Cellular Localization

Membrane,Nucleus,Cytoplasm

Background

This gene encodes a member of the regulator of G-protein signaling family. This protein contains a conserved, 120 amino acid motif called the RGS domain and a cysteine-rich region. The protein attenuates the signaling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Human RGS17 protein, His tag. GTX68384-pro

GTX68384-pro Image

3μg Human RGS17 protein (GTX68384-pro) by SDS-PAGE under reducing condition and visualized by coomassie blue stain.

REFERENCE

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SDS
Glycerol.pdf
Package List Price ($)
$ 289