APPLICATION
PROPERTIES
Form
Liquid
Buffer
50mM Tris/HCl (pH7.7), 150mM NaCl, 5mM DTT, 10% Glycerol
Preservative
No preservative
Storage
Store as concentrated solution. Aliquot and store at -20ºC or below. Avoid freeze-thaw cycles.
Concentration
Batch dependent (Please refer to the vial label for the specific concentration.)
Region/Sequence
Full-length protein, His-Tag; NP_000627.2
Expression System
E. coli
Purification
Affinity Purified
Purity
> 90%
Conjugation
Unconjugated
Note
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET
Synonyms
superoxide dismutase 2 , IPO-B , IPOB , MNSOD , MVCD6 , Mn-SOD
Background
This gene is a member of the iron/manganese superoxide dismutase family. It encodes a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. This protein binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in this gene have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 1. [provided by RefSeq, Apr 2016]
Database
Research Area
DATA IMAGES
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GTX00444-pro Image
SDS-PAGE analysis of GTX00444-pro Human SOD2 protein.
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REFERENCE
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REVIEW
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