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ICAM1 / CD54 antibody [15.2]

Cat. No. GTX20020

Reference 15

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 15.2

Isotype

 IgG1

Application

 WB, ICC/IF, IHC-P, IHC-Fr, FACS, IP, ELISA, Blocking, Neutralizing/Inhibition

Reactivity

 Human, Mouse, Rabbit, Pig
Package
100 μg ($399)
See all ICAM1 / CD54 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB Assay dependent
ICC/IF Assay dependent
IHC-P Assay dependent
IHC-Fr Assay dependent
FACS ≤ 1μg/10⁶ cells
IP Assay dependent
ELISA Assay dependent
Blocking Assay dependent
Neutralizing/Inhibition Assay dependent

Note :

FACS
The suggested use of these reagents is in a final volume of 100 μL.
Not tested in other applications.

Calculated MW

58 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

Borate buffered saline

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Concentration

0.1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Rheumatoid synovial cells and human monocytes

Purification

Purified IgG1

Conjugation

Unconjugated

RRID

AB_423825

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

intercellular adhesion molecule 1 , BB2 , CD54 , P3.58

Cellular Localization

Membrane; Single-pass type I membrane protein

Background

This gene encodes a cell surface glycoprotein which is typically expressed on endothelial cells and cells of the immune system. It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also exploited by Rhinovirus as a receptor. [provided by RefSeq, Jul 2008]

Database

Research Area

REFERENCE

Application Reference

Eun-Ji Lim et al. Cell Death Dis 2022; 13 (4) : 417 ICAM-1 promotes cancer progression by regulating SRC activity as an adapter protein in colorectal cancer.
Chiang HY et al. J Biomed Sci 2019; 26 (1) : 61 MFG-E8 mediates arterial aging by promoting the proinflammatory phenotype of vascular smooth muscle cells.
Application : WB
Reactivity : Mouse
Lin JC et al. Neoplasia 2019; 21 (5) : 459-468 Musashi-1 Enhances Glioblastoma Migration by Promoting ICAM1 Translation.
Application : FACS
Reactivity : Human
Fan JR et al. Cell Death Dis 2018; 9 (5) : 502 Potential role of CBX7 in regulating pluripotency of adult human pluripotent-like olfactory stem cells in stroke model.
Application : FACS
Reactivity : Human

Clone Reference

Lee TC et al. PLoS One 2014; 9 (11):e111390 Comparison of Surface Markers between Human and Rabbit Mesenchymal Stem Cells.
Application : FACS
Reactivity : Human, Rabbit
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REVIEW

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Application Reference
Eun-Ji Lim et al. Cell Death Dis 2022; 13 (4):417 ICAM-1 promotes cancer progression by regulating SRC activity as an adapter protein in colorectal cancer.
Chiang HY et al. J Biomed Sci 2019; 26 (1):61 MFG-E8 mediates arterial aging by promoting the proinflammatory phenotype of vascular smooth muscle cells.
Application : WB
Reactivity : Mouse
Lin JC et al. Neoplasia 2019; 21 (5):459-468 Musashi-1 Enhances Glioblastoma Migration by Promoting ICAM1 Translation.
Application : FACS
Reactivity : Human
Fan JR et al. Cell Death Dis 2018; 9 (5):502 Potential role of CBX7 in regulating pluripotency of adult human pluripotent-like olfactory stem cells in stroke model.
Application : FACS
Reactivity : Human
Tran DQ et al. J Immunol 2009; 182 (5):2929-38 Analysis of adhesion molecules, target cells, and role of IL-2 in human FOXP3+ regulatory T cell suppressor function.
Application : Blocking
Reactivity : Mouse
Clone Reference
Lee TC et al. PLoS One 2014; 9 (11):e111390 Comparison of Surface Markers between Human and Rabbit Mesenchymal Stem Cells.
Application : FACS
Reactivity : Human, Rabbit
2012; The transcription factor Erg controls endothelial cell quiescence by repressing activity of nuclear factor (NF)-κB p65
Application : WB
Reactivity : Human
2012; A restricted subset of var genes mediates adherence of Plasmodium falciparum-infected erythrocytes to brain endothelial cells
Application : Neutralizing/Inhibition
Reactivity : Human
2012; Multiple receptors trigger human NK cell-mediated cytotoxicity against porcine chondrocytes
Application : Neutralizing/Inhibition
Reactivity : Pig
2011; Endothelial reticulon-4B (Nogo-B) regulates ICAM-1-mediated leukocyte transmigration and acute inflammation
Application : Neutralizing/Inhibition
Reactivity : Human
2010; Perturbation of adhesion molecule-mediated chondrocyte-matrix interactions by 4-hydroxynonenal binding: implication in osteoarthritis pathogenesis
Application : FACS
Reactivity : Human
2009; Fibrinogen binding to ICAM-1 promotes EGFR-dependent mucin production in human airway epithelial cells
Application : Neutralizing/Inhibition
Reactivity : Human
2005; Effect of long-term culture on the expression of antigens and adhesion molecule in single porcine pancreatic endocrine cells
Application : IHC-P
Reactivity : Pig
2000; Human bronchial intraepithelial T lymphocytes as a distinct T-cell subset: their long-term survival in SCID-Hu chimeras
Application : IHC-Fr
Reactivity : Human
1997; Contribution of virion ICAM-1 to human immunodeficiency virus infectivity and sensitivity to neutralization
Application : IP
Package List Price ($)
$ 399