*Optimal dilutions/concentrations should be determined by the researcher.
Not tested in other applications.
Positive control lysate: A375M melanoma cell line or tonsil 85-115 kDa MW
P1W16 may be useful for prognosis of malignant melanoma.
Preservative: None. Constituents: PBS
Cell preparation: V(+)B2- Human Ocular melanoma line.
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Major group rhinovirus receptor, BB2, intercellular adhesion molecule 1, cell surface glycoprotein P3.58, CD54, human rhinovirus receptor, ICAM1, intercellular adhesion molecule1, P3.58
Type I membrane protein
ICAM1 is a 85-110 kDa single-chain type 1 integral membrane glycoprotein with an extracellular domain of five immunoglobulin superfamily repeats, a transmembrane region and a cytoplasmic domain. It shares considerable amino acid sequence homology with ICAM3 and with ICAM2. ICAM1 is expressed by activated endothelial cells. It is detected on cells of many other lineages (e.g. epithelial cells, fibroblasts, chondrocytes, B lymphocytes, T lymphocytes (low), monocytes, macrophages, dendritic cells and neutrophils, with lower levels that increase in inflammation. Also, ICAM1 is detected in some carcinoma and melanoma cells. Soluble ICAM1 is detectable in the plasma and is elevated in patients with various inflammatory syndromes. It is the receptor for rhinoviruses and malaria.