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IL10 antibody

Anti-IL10 antibody used in IHC (Paraffin sections) (IHC-P). GTX37657
Anti-IL10 antibody used in IHC (Paraffin sections) (IHC-P). GTX37657
Anti-IL10 antibody used in IHC (Paraffin sections) (IHC-P). GTX37657

Cat. No. GTX37657

Reference 1

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 IHC-P

Reactivity

 Human, Rat, Dog
Package
100 μg ($459)
See all IL10 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1:400-800
Not tested in other applications.

Calculated MW

21 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

0.01M TBS, 0.5% BSA, 25% Glycerol

Preservative

0.015% ProClin 300

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.5 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

KLH conjugated synthetic peptide derived between 111-168 amino acids of human IL10

Purification

Protein A purified

Conjugation

Unconjugated

RRID

AB_11172270

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

interleukin 10 , CSIF , GVHDS , IL-10 , IL10A , TGIF

Cellular Localization

Secreted

Background

The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis.[provided by RefSeq, May 2011]

Database

Research Area

DATA IMAGES

Anti-IL10 antibody used in IHC (Paraffin sections) (IHC-P). GTX37657

GTX37657 IHC-P Image

IHC-P analysis of rat kidney tissue using GTX37657 IL10 antibody.
Dilution : 1:200

Anti-IL10 antibody used in IHC (Paraffin sections) (IHC-P). GTX37657

GTX37657 IHC-P Image

IHC-P analysis of dog ureter tissue using GTX37657 IL10 antibody.

Anti-IL10 antibody used in IHC (Paraffin sections) (IHC-P). GTX37657

GTX37657 IHC-P Image

IHC-P analysis of human colon tissue using GTX37657 IL10 antibody.

REFERENCE

Application Reference

Wei CC et al. EBioMedicine 2018; 28 : 274-286 Allergic Conjunctivitis-induced Retinal Inflammation Promotes Myopia Progression.
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REVIEW

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SDS
Glycerol.pdf
Proclin.pdf
Package List Price ($)
$ 459