GeneTex
United States (US)

IL13 recombinant protein

Cat No. GTX65457

Application ELISA, Functional Assay, Apuri, Blocking
Reactivity Rat
Species Rat
APPLICATION

Application Note

The ED50 as determined by the dose-dependent stimulation of the proliferation of human TF-1 cells was typically 2-6 ng/ml.

Calculated MW

12.7 kDa. ( Note )
PROPERTIES

Form

Lyophilized powder

Storage

Reconstitute in water to a concentration of 0.1-1.0 mg/ml. The solution can then be diluted into other aqueous buffers. Store at -20ºC.

Antigen Species

Rat

Expression System

E. coli

Purification


Purity was assessed by SDS-PAGE (≥95%) and by HPLC (≥95%).

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

P600, NC30, IL-13, BHR1, ALRH, IL13, MGC116788, MGC116789., MGC116786, IL 13

Background

IL-13 is an immunoregulatory cytokine produced mainly by T helper 2 cells, but also by mast cells and NK cells. IL-13 is a unique cytokine having similar structural features and functional characteristics as IL-4, but only shares ~30% homolog with the IL-4 sequence. IL-13 inhibits IL-1beta, IL-6, IL-8, and TNF-alpha resulting in anti-inflammatory effects on monocytes and macrophages. IL-13 also induces B cells to proliferate and modulating TH2 cell development. Recombinant rat IL-13 is an 11.9 kDa protein containing 109 amino acid residues.
Package List Price ($)
$ 249