GeneTex
United States (US)

IL16 protein

Cat No. GTX29564

Reactivity Human
Species Human
PROPERTIES

Form

Liquid

Buffer

Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1 mg/ml.

Storage

Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles.

Antigen Species

Human

Expression System

E. coli

Purification


Sterile filtered Greater than 98% pure by SDS-PAGE and HPLC analyses. Endotoxin level is less than 0.1 ng per μg (1EU/μg).

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Interleukin 16,Lcf,Nil16,Pril16,Pril-16,Il16

Cellular Localization

Secreted

Background

IL16, also known as lymphocyte chemoattractant factor (LCF), is a proinflammatory cytokine that is chemotactic for CD4+ T lymphocytes, monocytes, and eosinophils. It was originally identified as a CD8+ T cell derived chemoattractant for CD4+ cells. The biologically active form of IL16, originally proposed to be a homotetramer of 14 kDa chains with 130 amino acid residues, is now believed to have been derived from the C terminus of the precursor molecule. Subsequently, IL16 is synthesized as a precursor molecule (pro IL16) of approximately 68 kDa and 631 amino acid residues lacking a signal peptide. The sequence and structure of IL16 is conserved across species. Structurally and functionally, particularly in the C terminal region, human and mouse IL16 share approximately 82 % similarity.

Research Area

Package List Price ($)
$ 299