GeneTex
United States (US)

IL2 protein

Cat No. GTX29619

Reactivity Human
Species Human
PROPERTIES

Form

Lyophilized powder

Storage

The lyophilized protein is stable for a few weeks at room temperature, but best stored at -20 ºC. We recommend a quick spin followed by reconstitution in 100 mM acetic acid to a concentration of 0.1-1.0mg/ml. This solution can then be diluted into ot

Antigen Species

Human

Immunogen

Recombinant full length protein (>98% pure by SDS-PAGE): MAPTSSSTKKTQLQLEHLLLDLQMILNGINNYKNPKLTRMLTFKFYMPKKATELKHLQCLEEELKPLEEVLNLAQSKNFHLRPRDLISNINVIVLELKGSETTFMCEYADETATIVEFLNRWITFCQSIISTLT (Human).

Region/Sequence

Recombinant full length protein (>98% pure by SDS-PAGE): MAPTSSSTKKTQLQLEHLLLDLQMILNGINNYKNPKLTRMLTFKFYMPKKATELKHLQCLEEELKPLEEVLNLAQSKNFHLRPRDLISNINVIVLELKGSETTFMCEYADETATIVEFLNRWITFCQSIISTLT (Human).

Purification


Sterile filtered. Greater than 97% pure by SDS-PAGE and HPLC analyses. Endotoxin level is less than 0.1ng per μg (1EU/μg).

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Interleukin 2,Il-2,Tcgf,Lymphokine,Il2

Cellular Localization

Secreted

Background

Human interleukin 2 (IL2) is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli.

Research Area

Package List Price ($)
$ 299