GeneTex
United States (US)

Integrin alpha 3 antibody [IA3]

Cat No. GTX40141

Host Mouse
Clonality Monoclonal
Clone Name IA3
Isotype IgG1
Application IHC-Fr, IHC-F
Reactivity Human
APPLICATION

Application Note

FuncS: Use at an assay dependent dilution. IHC-Fr: Use at an assay dependent dilution. Optimal dilutions/concentrations should be determined by the end user.

Calculated MW

117 kDa. ( Note )

Specificity/Sensitivity

Specific to alpha 3 integrin. IA3 is useful for studies on inhibition of cell-cell adhesion and cell-substrate adhesion.
PROPERTIES

Form

Liquid

Buffer

Phosphate-buffered saline

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1.2 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Cell preparation: Transfected human breast epithelial cell line MTSV1-7, hygromycin resistant

Purification

IgG fraction

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Integrin Subunit Alpha 3,Cd49C,Frp-2,Gap-B3,Gapb3,Ilneb,Msk18,Vca-2,Vl3A,Vla3A,Itga3

Cellular Localization

Cell Membrane

Background

Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 3 undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 to form an integrin that interacts with many extracellular-matrix proteins. The alpha 3 beta 1 integrin is known variously as: very late (activation) antigen 3 (VLA3), very common antigen 2 (VCA2), extracellular matrix receptor 1 (ECMR1), and galactoprotein b3 (GAPB3).

Database

Research Area

Package List Price ($)
$ 319