GeneTex
United States (US)

Integrin alpha V antibody [272-17E6]

Cat No. GTX16821

Host Mouse
Clonality Monoclonal
Clone Name 272-17E6
Isotype IgG1
Application FACS, IP, ELISA, IHC
Reactivity Human
APPLICATION

Application Note

For ELISA: Use at an assay dependent dilution. For FACS, IHC-P and IP: Use at a concentration of 2 - 3μg/ml. Optimal dilutions/concentrations should be determined by the researcher.

Calculated MW

116 kDa. ( Note )

Specificity/Sensitivity

Cross reacts with all alpha V integrins.
PROPERTIES

Form

Liquid

Buffer

PBS, pH 7.6, no preservatives added

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.5 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Full length native protein (purified) (Human).

Purification

Purified IgG

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Integrin Subunit Alpha V,Cd51,Msk8,Vnra,Vtnr,Itgav

Cellular Localization

Cell Membrane

Background

Integrin alpha V chain interacts with the integrin beta 3 subunit/CD61 to form the alpha-V-beta-3 heterodimer/vitronectin receptor. It is expressed on endothelial cells, some activated leukocytes, NK cells, macrophages, neutrophils, and platelets. Integrin alpha V also forms heterodimers with the integrin beta 1, beta 5, beta 6, and beta 8 subunits. Alpha-V-beta-3 is an activation dependent receptor for platelet attachment and spreading on vitronectin and other matrix components.

Database

Research Area

Package List Price ($)
$ 449