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KCNH6 antibody

Anti-KCNH6 antibody used in IHC (Frozen sections) (IHC-Fr). GTX16688
Anti-KCNH6 antibody used in Western Blot (WB). GTX16688

Cat. No. GTX16688

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-Fr

Reactivity

 Human, Mouse, Rat
Package
50 μl ($639)
See all KCNH6 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB Assay dependent
IHC-Fr Assay dependent
Not tested in other applications.

Calculated MW

110 kDa. ( Note )

Predict Reactivity

Chicken(>80% identity)

PROPERTIES

Form

Liquid

Buffer

PBS, 1% BSA

Preservative

0.025% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.75 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Peptide TLNFVEFNLEKHRS(C), corresponding to amino acid residues 185-198 (  Intracellular, N-terminal part) of human Kv11.2 (Accession  : Q9H252).

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

potassium voltage-gated channel subfamily H member 6 , ERG-2 , ERG2 , HERG2 , Kv11.2 , hERG-2

Cellular Localization

Membrane; Multi-pass membrane protein

Background

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit. Alternative splicing results in multiple transcript variants that encode different isoforms. [provided by RefSeq, Jul 2013]

Database

Research Area

DATA IMAGES

Anti-KCNH6 antibody used in IHC (Frozen sections) (IHC-Fr). GTX16688

GTX16688 IHC-Fr Image

IHC-Fr analysis of rat hippocampus tissue using GTX16688 KCNH6 antibody.
Panel A :  Kv11.2 appears as diffuse staining (green) that defines the boundary of the reticular nucleus of thalamus (arrow).
Panel B : Staining with mouse anti-parvalbumin (PV, red) demonstrates both neuronal and diffuse staining.
Panel C : Merge of KV11.2 and PV demonstrates overlap of the two markers labeling the reticular nucleus of the thalamus (orange).

Anti-KCNH6 antibody used in Western Blot (WB). GTX16688

GTX16688 WB Image

WB analysis of rat brain (1 and 3) and rat cortex ( 2 and 4) lysates using GTX16688 KCNH6 antibody preincubated with or without immunogen peptide.
Dilution : 1:200

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 639