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Kappa Opioid Receptor antibody

Anti-Kappa Opioid Receptor antibody used in Western Blot (WB). GTX108164

Cat. No. GTX108164

Reference 2

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB

Reactivity

 Human
Package
100 μl ($399),
25 μl ($169)
See all Kappa Opioid Receptor products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500-1:3000
Not tested in other applications.

Calculated MW

43 kDa. ( Note )

Positive Control

HepG2 , Raji

Predict Reactivity

Mouse, Rat, Dog, Rhesus Monkey(>80% identity)

PROPERTIES

Form

Liquid

Buffer

0.1M Tris, 0.1M Glycine, 10% Glycerol

Preservative

0.01% Thimerosal

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.91 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic peptide encompassing a sequence within the Extracellular domain of human Kappa Opioid Receptor. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

RRID

AB_1951064

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

opioid receptor kappa 1 , K-OR-1 , KOR , KOR-1 , OPRK

Cellular Localization

Cell membrane; Multi-pass membrane protein

Background

Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Receptor for dynorphins. May play a role in arousal and regulation of autonomic and neuroendocrine functions.

Database

Research Area

DATA IMAGES

Anti-Kappa Opioid Receptor antibody used in Western Blot (WB). GTX108164

GTX108164 WB Image

Sample (30 ug of whole cell lysate)
A: Hep G2 (GTX27900)
B: Raji
10% SDS PAGE
GTX108164 diluted at 1:1000

REFERENCE

Application Reference

Zhao H et al. Cell Rep 2022; 38 (4) : 110253 Opioid receptor signaling suppresses leukemia through both catalytic and non-catalytic functions of TET2.
Cui Y et al. Lipids Health Dis 2019; 18 (1) : 52 κ-Opioid receptor stimulation reduces palmitate-induced apoptosis via Akt/eNOS signaling pathway.
Application : WB
Reactivity : Human
Submit a Reference

REVIEW

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SDS
Glycerol.pdf
Thimerosal.pdf
Package List Price ($)
$ 399
$ 169