GeneTex
United States (US)

LH beta antibody

Cat No. GTX39803

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IHC-Fr
Reactivity Human
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1/300-1/400
IHC-Fr Assay dependent
Not tested in other applications.

Calculated MW

15 kDa. ( Note )

Specificity/Sensitivity

This antibody reacts with the beta subunit of chorionic gonadotropin. Some reactivity has been observed with human TSH, FSH and prolactin.
PROPERTIES

Form

Liquid

Buffer

Ammonium bicarbonate

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Human beta luteinizing hormone

Purification

Ammonium sulphate precipitation

Conjugation

Unconjugated

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

LSH-B Antibody , LHB Antibody , CGB4 Antibody , HLHB Antibody

Background

This gene is a member of the glycoprotein hormone beta chain family and encodes the beta subunit of luteinizing hormone (LH). Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. LH is expressed in the pituitary gland and promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids. The genes for the beta chains of chorionic gonadotropin and for luteinizing hormone are contiguous on chromosome 19q13.3. Mutations in this gene are associated with hypogonadism which is characterized by infertility and pseudohermaphroditism. [provided by RefSeq, Jul 2008]
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Database

Research Area