GeneTex
United States (US)

LTBR antibody [Carlos-1]

Cat No. GTX16094

Host Rat
Clonality Monoclonal
Clone Name Carlos-1
Isotype IgG2a
Application FACS, IP
Reactivity Human
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
FACS 1:1,000
IP 1:200

Note :

FACS
HEK 293T cells (5 x 10?) were mock transfected or transfected with LTβR?.

Not tested in other applications.

Calculated MW

47 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

PBS with 0.02% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Fusion protein, corresponding to amino acids 28 - 220 (the cysteine-rich region) of Human LTBR fused to the Fc portion of human IgG1.

Purification

Purified IgG2a
From tissue culture supernatant

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Lymphotoxin Beta Receptor,D12S370,Lt-Beta-R,Tnf-R-Iii,Tnfcr,Tnfr-Rp,Tnfr2-Rp,Tnfr3,Tnfrsf3,Ltbr

Cellular Localization

Type I membrane protein.

Background

The protein encoded by this gene is a member of the tumor necrosis factor (TNF) family of receptors. It is expressed on the surface of most cell types, including cells of epithelial and myeloid lineages, but not on T and B lymphocytes. The protein specifically binds the lymphotoxin membrane form (a complex of lymphotoxin-alpha and lymphtoxin-beta). The encoded protein and its ligand play a role in the development and organization of lymphoid tissue and tranformed cells. Activation of the encoded protein can trigger apoptosis.

Database

Research Area

Package List Price ($)
$ 319