GeneTex
United States (US)

MAdCAM-1 antibody

GTX12305_20160104_IHC-P_18121410_508.jpg
GTX12305_20160104_IHC-Fr_18121410_855.jpg
GTX12305_20160104_WB_18121410_960.jpg

Cat No. GTX12305

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P, IHC-Fr
Reactivity Human
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB Assay dependent
IHC-P Assay dependent
IHC-Fr Assay dependent
Not tested in other applications.

Calculated MW

40 kDa kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

5% BSA, 0.9% NaCl, 0.2% Na2HPO4, 0.05% Thimerosal, 0.05% NaN3.

Concentration

0.50mg/ml

Antigen Species

Human

Immunogen

The immunogen corresponding to a region within amino acids 173 and 190 of human MAdCAM-1.

Purification

Immunogen affinity purified.

Conjugation

Unconjugated

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

mucosal vascular addressin cell adhesion molecule 1 Antibody, MACAM1 Antibody

Background

The protein encoded by this gene is an endothelial cell adhesion molecule that interacts preferentially with the leukocyte beta7 integrin LPAM-1 (alpha4beta7), L-selectin, and VLA-4 (alpha4beta1) on myeloid cells to direct leukocytes into mucosal and inflamed tissues. It is a member of the immunoglobulin family and is similar to ICAM1 and VCAM1. At least seven alternatively spliced transcripts encoding different protein isoforms have been found for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq, Jul 2008]
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Database

Research Area

DATA IMAGES
GTX12305_20160104_IHC-P_18121410_508.jpg

GTX12305 IHC-P Image

Anti-MAdCAM1 antibody, IHC(P)
IHC(P): Human Appendicitis Tissue

GTX12305_20160104_IHC-Fr_18121410_855.jpg

GTX12305 IHC-Fr Image

Anti-MAdCAM1 antibody, IHC(F)
IHC(F): Human Placenta Tissue

GTX12305_20160104_WB_18121410_960.jpg

GTX12305 WB Image

Anti-MAdCAM1 antibody, Western blotting
All lanes: Anti MAdCAM1 antibody at 0.5ug/ml
WB: HELA Whole Cell Lysate at 40ug
Predicted bind size: 40KD
Observed bind size: 40KD