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MCM7 antibody [MCM7/1466]

Anti-MCM7 antibody [MCM7/1466] used in Western Blot (WB). GTX34817
Anti-MCM7 antibody [MCM7/1466] used in IHC (Paraffin sections) (IHC-P). GTX34817
Anti-MCM7 antibody [MCM7/1466] used in Western Blot (WB). GTX34817

Cat. No. GTX34817

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 MCM7/1466

Isotype

 IgG2b

Application

 WB, IHC-P

Reactivity

 Human
Package
100 μg ($529)
See all MCM7 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1-2μg/ml
IHC-P 1-2μg/ml for 30 minutes at RT

Note :

IHC-P
Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95ºC followed by cooling at RT for 20 minutes.
Not tested in other applications.

Calculated MW

81 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

10mM PBS, 0.05% BSA

Preservative

0.05% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.2 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant human MCM7 protein fragment (aa195-319)

Purification

Protein A/G purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

CDC47 , MCM2 , MCM7 , P1.1MCM3 , P1CDC47 , P85MCM , PNAS146 , PPP1R104 , minichromosome maintenance complex component 7

Cellular Localization

Nucleus

Background

The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumorsuppressor protein RB1/RB. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-MCM7 antibody [MCM7/1466] used in Western Blot (WB). GTX34817

GTX34817 WB Image

WB analysis of MCF-7, HEK-293, A549 lysates using GTX34817 MCM7 antibody [MCM7/1466].

Anti-MCM7 antibody [MCM7/1466] used in IHC (Paraffin sections) (IHC-P). GTX34817

GTX34817 IHC-P Image

IHC-P analysis of human tonsil tissue using GTX34817 MCM7 antibody [MCM7/1466].

Anti-MCM7 antibody [MCM7/1466] used in Western Blot (WB). GTX34817

GTX34817 WB Image

WB analysis of (A) HeLa, (B) Raji, and (C) HepG2 cell lysates using GTX34817 MCM7 antibody [MCM7/1466].

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 529