GeneTex
United States (US)

MCP1 / CCL2 protein

Cat No. GTX29670

Reactivity Human
Species Human
PROPERTIES

Form

Lyophilized powder

Buffer

Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1 mg/ml.

Storage

Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles.

Antigen Species

Human

Expression System

E. coli

Purification


Sterile filtered. Greater than 99% by SDS-PAGE and HPLC analyses. Endotoxin level is less than 0.1 ng per μg (1EU/μg).

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

C-C Motif Chemokine Ligand 2,Gdcf-2,Hc11,Hsmcr30,Mcaf,Mcp-1,Mcp1,Scya2,Smc-Cf,Ccl2

Cellular Localization

Secreted

Background

This chemotactic factor attracts monocytes and basophils but not neutrophils or eosinophils and augments monocyte anti-tumor activity. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis or atherosclerosis. It may be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis.

Research Area