GeneTex
United States (US)

MCP1 / CCL2 recombinant protein

Cat No. GTX65374

Application ELISA, Functional Assay, Apuri, Blocking
Reactivity Mouse
Species Mouse
APPLICATION

Application Note

Protein's bioactivity determined by measuring the dose dependent chemotaxis with human THP-1 cells. The ED50 is in the range of 1-10 ng/ml

Calculated MW

13.8 kDa. ( Note )
PROPERTIES

Form

Lyophilized powder

Storage

Reconstitute in water to a concentration of 0.1-1 mg/ml. This solution can then be diluted into other aqueous buffers or stored at 4ºC for 1 week or –20ºC for future use.

Antigen Species

Mouse

Expression System

E. coli

Purification


Purity was assessed by SDS-PAGE (≥98%) and by HPLC (≥98%).

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Monocyte chemotactic protein1, SMC-CF, Monocyte chemotactic protein 1, MCP1, Monocyte chemotactic and activating factor, Immediate-early serum-responsive JE protein., Small inducible cytokine A2, GDCF-2, GDCF2, Immediateearly serumresponsive JE protein., SMCCF, MGC9434, Monocyte sec, SMC CF, GDCF 2

Background

Murine JE (also known as Macrophage/Monocyte Chemotactic Protein) is a 13.8 kDa protein containing 125 amino acid residues. It plays an important role in the inflammatory response of blood monocytes and tissue microphages.

Research Area