GeneTex
United States (US)

MCP4 recombinant protein

Cat No. GTX65242

Application ELISA, Functional Assay, Apuri, Blocking
Reactivity Human
Species Human
APPLICATION

Application Note

The specific activity as determined by the ability of MCP-4 to chemoattract human monocytes was achieved at 10-100 ng/ml.

Calculated MW

8.6 kDa. ( Note )
PROPERTIES

Form

Lyophilized powder

Buffer

Sterile filtered and then lyophilized from a concentrated (1mg/ml) sterile solution containing 20 mM phosphate buffer, pH 7.4 and 130 mM NaCl.

Storage

Reconstitute in water to a concentration of not less than 0.1 mg/ml. This solution can be diluted into other buffered solutions or stored at –20ºC for future use.

Antigen Species

Human

Expression System

E. coli

Purification


Purity was assessed by SDS-PAGE (≥95%) and by HPLC (≥95%).

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Monocyte Chemotactic Protein4, NCC-1, Monocyte Chemotactic Protein-4, CCL13, NCC1, MCP4, NCC 1, Monocyte Chemotactic Protein 4

Background

Human macrophage/monocyte chemotactic protein-4 (MCP-4) is a member of the beta chemokine family (C-C) of cytokines. Like eotaxin, MCP-4 is a powerful eosinophil chemoattractant. Additionally, like MCP-3, MCP-4 elicits chemoattraction of monocytes and T lymphocytes. MCP-4 is a peptide of 8.6 kDa that consists of 75 amino acid residues.

Research Area