GeneTex

  • Country / Location Selection

United States (US)

MDC antibody

Cat. No. GTX10379

Host

 Chicken

Clonality

 Polyclonal

Isotype

 IgY

Application

 WB, ELISA

Reactivity

 Human
Package
25 μg ($399)
See all MDC products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 0.1-0.2 μg/ml
ELISA 0.5-1.0 μg/ml
Not tested in other applications.

Calculated MW

11 kDa. ( Note )

Product Note

The antibody shows 20% cross-reactivity with recombinant human MPIF-1, 10% cross-reactivity with recombinant human MIP-1δ and 1% cross-reactivity with recombinant mouse MDC, human HCC-1, human I-309, mouse MIP-1α, viral MIP-I, mouse MIP-1β and mouse MIP-1γ.

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

recombinant human MDC expressed in E. coli.

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

C-C motif chemokine ligand 22 , A-152E5.1 , ABCD-1 , DC/B-CK , MDC , SCYA22 , STCP-1

Cellular Localization

Secreted

Background

MDC is a member of the beta (CC) chemokine family and induces chemotaxis or calcium mobilization in dendritic cells, IL-2 activated cells and activated T lymphocytes. MDC, also named stimulated T cell chemotactic protein (STCP-1), was isolated from clones of monocyted-derived macrophages and binds to CC chemokine receptor 4 (CCR4). MDC shows less than 35% identity to other C-C chemokine family members. It is expressed in dendritic cells, macrophages and activated monocytes. Expression is also detected in the tissues of thymus, lymph node and appendix. NH2- terminally truncated forms of natural MDC were isolated from a CD8+ T cell clone and have been reported to inhibit HIV-1 infection.

Database

Research Area

REFERENCE

There are currently no references for MDC antibody (GTX10379). Be the first to share your publications with this product.
Submit a Reference

REVIEW

There are currently no reviews for MDC antibody (GTX10379). Be the first to share your experience with this product.
Submit a Review
SDS
PBS.pdf
Package List Price ($)
$ 399