APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| 5-10μg/ml |
|
Note :
IHC-P
Positive staining seen Human Testis and Human Brain Cortex.
|
Not tested in other applications.
Calculated MW
Positive Control
The peptide used to generate this antibody is available for purchase (GTX89763-PEP).
Predict Reactivity
Mouse, Rat, Dog, Pig(>80% identity)
PROPERTIES
Form
Liquid
Buffer
TBS, 0.5% BSA
Preservative
0.02% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
0.50 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Peptide with sequence CNCGAKRCRRFLN, from the C Terminus of the protein sequence according to NP_055542.1.
Purification
Purified by ammonium sulphate precipitation followed by antigen affinity chromatography
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
lysine methyltransferase 2B , CXXC10 , DYT28 , HRX2 , MLL1B , MLL2 , MLL4 , TRX2 , WBP-7 , WBP7
Cellular Localization
Nucleus
Background
This gene encodes a protein which contains multiple domains including a CXXC zinc finger, three PHD zinc fingers, two FY-rich domains, and a SET (suppressor of variegation, enhancer of zeste, and trithorax) domain. The SET domain is a conserved C-terminal domain that characterizes proteins of the MLL (mixed-lineage leukemia) family. This gene is ubiquitously expressed in adult tissues. It is also amplified in solid tumor cell lines, and may be involved in human cancer. Two alternatively spliced transcript variants encoding distinct isoforms have been reported for this gene, however, the full length nature of the shorter transcript is not known. [provided by RefSeq, Jul 2008]
Database
Research Area
DATA IMAGES
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GTX89763 IHC-P Image
IHC-P analysis of human cortex using GTX89763 MLL4 antibody, C-term.
Antigen retrieval : citrate buffer pH 6
Dilution : 5μg/ml
|
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GTX89763 IHC-P Image
IHC-P analysis of human testis using GTX89763 MLL4 antibody, C-term.
Antigen retrieval : citrate buffer pH 6
Dilution : 5μg/ml
|
REFERENCE
There are currently no references for MLL4 antibody, C-term (GTX89763). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for MLL4 antibody, C-term (GTX89763). Be the first to share your experience with this product.
