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MLL4 antibody

Anti-MLL4 antibody used in Western Blot (WB). GTX55187

Cat. No. GTX55187

Reference 1

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB

Reactivity

 Human, Mouse, Rat
Package
100 μl ($399)
See all MLL4 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:1000
Not tested in other applications.

Calculated MW

294 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

0.42% Potassium Phosphate, 0.87% NaCl, 30% Glycerol

Preservative

0.01% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

KLH-conjugated synthetic peptide encompassing a sequence within the center region of MLL4. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

RRID

AB_2887918

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

lysine methyltransferase 2B , CXXC10 , DYT28 , HRX2 , MLL1B , MLL2 , MLL4 , TRX2 , WBP-7 , WBP7

Cellular Localization

Nucleus

Background

This gene encodes a protein which contains multiple domains including a CXXC zinc finger, three PHD zinc fingers, two FY-rich domains, and a SET (suppressor of variegation, enhancer of zeste, and trithorax) domain. The SET domain is a conserved C-terminal domain that characterizes proteins of the MLL (mixed-lineage leukemia) family. This gene is ubiquitously expressed in adult tissues. It is also amplified in solid tumor cell lines, and may be involved in human cancer. Two alternatively spliced transcript variants encoding distinct isoforms have been reported for this gene, however, the full length nature of the shorter transcript is not known. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-MLL4 antibody used in Western Blot (WB). GTX55187

GTX55187 WB Image

WB analysis of HL60 (A), A549 (B), NIH3T3 (C), H9C2 (D) whole cell lysates using GTX55187 MLL4 antibody.

REFERENCE

Application Reference

Imuta H et al. Heart Vessels 2020; Histone methylation and demethylation are implicated in the transient and sustained activation of the interleukin-1β gene in murine macrophages.
Application : WB
Reactivity : Mouse
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SDS
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399