GeneTex
United States (US)

MRCK beta (Active) recombinant protein

Cat No. GTX65307

Application ELISA, Functional Assay, Apuri, Blocking
Reactivity Human
Species Human
APPLICATION

Application Note

The specific activity of MRCKB was determined to be 120 nmol /min/mg as per activity assay protocol.

Calculated MW

73.0 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol.

Storage

Store at -80ºC. Product is stable for at least 6-12 months.

Concentration

0.1mg/ml(Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Expression System

Baculovirus (Sf9 insect cells)

Purification


Purity was assessed by SDS-PAGE (≥90%) and by HPLC.

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Cdc42 Binding Protein Kinase Beta,Mrckb,Cdc42Bpb

Background

Myotonic Dystrophy Kinase-Related cdc42-binding kinase beta (MRCKb) belongs to the DMPK subfamily (1). The myotonic dystrophy kinase-related kinases and myotonic dystrophy kinase-related Cdc42 binding kinase (MRCK) are effectors of RhoA and Cdc42, respectively, where they are involved in actin cytoskeletal reorganization and neurite outgrowth (2). Effects of the repeat expansion on the DMPK gene may be responsible for muscle and heart features of Myotonic Dystrophy.

Research Area

Package List Price ($)
$ 349