GeneTex
United States (US)

Mouse Caspase 3 (proform) protein

Cat No. GTX65331-pro

Species Mouse
APPLICATION

Calculated MW

31.48 kDa. ( Note )
PROPERTIES

Form

Lyophilized powder

Buffer

Reconstitute with PBS, 15% Glycerol to 0.1 mg/ml.

Storage

Store at -20ºC or below. After reconstitution, keep as concentrated solution. Aliquot and avoid freeze-thaw cycles.

Expression System

E. coli

Purity

≥ 90% by SDS-PAGE and HPLC.

Conjugation

Unconjugated

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

caspase 3 , A830040C14Rik , AC-3 , CASP-3 , CC3 , CPP-32 , CPP32 , Caspase-3 , Lice , SCA-1 , Yama , mldy

Background

This gene encodes a protein that belongs to a highly conserved family of cysteinyl aspartate-specific proteases that function as essential regulators of programmed cell death through apoptosis. Members of this family contain an N-terminal pro-domain and require cleavage at specific aspartate residues to become mature. The protein encoded by this gene belongs to a subgroup of cysteinyl aspartate-specific proteases that are activated by initiator caspases and that perform the proteolytic cleavage of apoptotic target proteins. Mice defective for this gene exhibit a variety of phenotypes including reduced neuronal apoptosis resulting in hyperplasias, hearing loss, attenuated osteogenic differentiation of bone marrow stromal stem cells, and pre- and post-natal lethality. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]

Database

Package List Price ($)
$ 349