GeneTex
United States (US)

NAK antibody

GTX31658_252_ICC-IF_20180221_18121410_736.jpg

Cat No. GTX31658

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, ICC/IF, ELISA
Reactivity Human, Mouse
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB Assay dependent
ICC/IF 10 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

84 kDa. ( Note )

Positive Control

MOLT-4 Cell Slide(GTX25537) , MOLT4 Cell Lysate(GTX27912)

Specificity/Sensitivity

No cross response to IKKa, IKKb, IKKy, or IKKe.
PROPERTIES

Form

Liquid

Buffer

PBS with 0.02% sodium azide.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

NAK antibody was raised against a synthetic peptide corresponding to 17 amino acids form near the carboxy terminus of human NAK/TBK1.The immunogen is located within the last 50 amino acids of NAK.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Tank Binding Kinase 1,Ftdals4,Iiae8,Nak,T2K,Tbk1

Background

The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation and nuclear translocation of the NFKB complex. The protein encoded by this gene is similar to IKB kinases and can mediate NFKB activation in response to certain growth factors. [provided by RefSeq, Oct 2010]

Database

Research Area

DATA IMAGES
GTX31658_252_ICC-IF_20180221_18121410_736.jpg

GTX31658 ICC/IF Image

ICC/IF analysis of MOLT4 cells using GTX31658 NAK antibody.
Working concentration : 10 μg/ml

Package List Price ($)
$ 329