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NALP6 antibody

Anti-NALP6 antibody used in Western Blot (WB). GTX85157
Anti-NALP6 antibody used in IHC (Paraffin sections) (IHC-P). GTX85157

Cat. No. GTX85157

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P, ELISA

Reactivity

 Human
Package
100 μg ($409)
See all NALP6 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1 μg/mL
IHC-P 20 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

99 kDa. ( Note )

Positive Control

Human Brain Tissue Slide(GTX22203) , Human Heart Tissue Lysate(GTX27916)

Predict Reactivity

Mouse, Rat(>80% identity)

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

NALP6 antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human NALP6.The immunogen is located within amino acids 150 - 200 of NALP6.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

NLR family pyrin domain containing 6 , AVR , CLR11.4 , NALP6 , NAVR , NAVR/AVR , PAN3 , PYPAF5

Cellular Localization

Cytoplasm,Cell membrane

Background

NALP proteins include the apoptosis regulator APAF1 (apoptotic protease activating factor 1) and mammalian NOD-LRR proteins and are thought to be involved in inflammation and reproduction. NALP6, also known as PYPAF5, is highly expressed in granulocytes and T cells and co-localizes with the PYRIN-CARD protein ASC. Co-expression of NALP6 with ASC results in a synergistic activation of NF-kB and activated caspase-1-dependent cytokine processing, suggesting that NALP6 functions in immune cells to coordinate the transduction of pro-inflammatory signals.

Database

Research Area

DATA IMAGES

Anti-NALP6 antibody used in Western Blot (WB). GTX85157

GTX85157 WB Image

WB analysis of various samples using GTX85157 NALP6 antibody.
Dilution : 2 μg/ml

Anti-NALP6 antibody used in IHC (Paraffin sections) (IHC-P). GTX85157

GTX85157 IHC-P Image

IHC-P analysis of human brain tissue using GTX85157 NALP6 antibody.
Working concentration : 20 μg/ml

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 409