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NKIRAS1 antibody [184C278]

Anti-NKIRAS1 antibody [184C278] used in Western Blot (WB). GTX13666

Cat. No. GTX13666

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 184C278

Isotype

 IgG1

Application

 WB

Reactivity

 Human, Mouse, Rat, Bovine, Dog, Pig, Horse, Xenopus, Primate
Package
100 μg ($399)
See all NKIRAS1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 0.5 - 1 μg/ml
Not tested in other applications.

Calculated MW

22 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 0.2% Gelatin

Preservative

0.05% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.5 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

This monoclonal antibody was raised against a synthetic peptide containing amino acid residues 96-113 (RVELLKKEIDKFKDKKEV) of human kB-Ras1.

Purification

Protein G purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

NFKB inhibitor interacting Ras like 1 , KBRAS1 , kappaB-Ras1

Cellular Localization

Cytoplasm

Background

Atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation. May act by blocking phosphorylation of NFKBIB and mediating cytoplasmic retention of p65/RELA NF-kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP- and GDP-bound forms block phosphorylation of NFKBIB.

Database

Research Area

DATA IMAGES

Anti-NKIRAS1 antibody [184C278] used in Western Blot (WB). GTX13666

GTX13666 WB Image

WB analysis of 293 cell lysate using GTX13666 NKIRAS1 antibody [184C278].
Dilution : 0.5 μg/ml

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399