APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
1:500 - 1:2000 |
1:50 - 1:200 |
Not tested in other applications.
Calculated MW
PROPERTIES
Form
Liquid
Buffer
PBS, 50% Glycerol
Preservative
0.02% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
Batch dependent (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 283-570 of human NOX2 / gp91phox (NP_000388.2).
Purification
Purified by affinity chromatography
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
AMCBX2 , CGD , CYBB , GP911 , GP91PHOX , IMD34 , NOX2 , cytochrome b245 beta chain , p91PHOX , gp91phox , cytochrome B245 heavy chain , gp91-phox , Cytochrome B245 beta , cytochrome b-245 beta chain
Cellular Localization
Cell membrane
Background
Cytochrome b (-245) is composed of cytochrome b alpha (CYBA) and beta (CYBB) chain. It has been proposed as a primary component of the microbicidal oxidase system of phagocytes. CYBB deficiency is one of five described biochemical defects associated with chronic granulomatous disease (CGD). In this disorder, there is decreased activity of phagocyte NADPH oxidase; neutrophils are able to phagocytize bacteria but cannot kill them in the phagocytic vacuoles. The cause of the killing defect is an inability to increase the cell's respiration and consequent failure to deliver activated oxygen into the phagocytic vacuole. [provided by RefSeq, Jul 2008]
Database
Research Area
DATA IMAGES
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GTX00785 IHC-P Image
IHC-P analysis of rat bone marrow tissue using GTX00785 NOX2 / gp91phox antibody. Dilution : 1:200
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GTX00785 WB Image
WB analysis of various sample lysates using GTX00785 NOX2 / gp91phox antibody. Dilution : 1:1000 Loading : 25μg per lane
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REFERENCE
There are currently no references for NOX2 / gp91phox antibody (GTX00785). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for NOX2 / gp91phox antibody (GTX00785). Be the first to share your experience with this product.