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OATP2 antibody [ESL]

Cat. No. GTX15441

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 ESL

Isotype

 IgM

Application

 WB, ICC/IF, IP

Reactivity

 Human
Package
100 μl ($399)
See all OATP2 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:1000
ICC/IF 1:100
IP Assay dependent
Not tested in other applications.

Calculated MW

76 kDa. ( Note )

Product Note

This antibody shows no cross-reactivity to other OATP isoforms.

PROPERTIES

Form

Liquid

Buffer

Tissue culture supernatant

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Synthetic peptide corresponding to residues E(671) S L N K N K H F V P S A G A D S E T H C(691) of human OATP2.

Purification

Unpurified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

solute carrier organic anion transporter family member 1B1 , HBLRR , LST-1 , LST1 , OATP-C , OATP1B1 , OATP2 , OATPC , SLC21A6

Background

This gene encodes a liver-specific member of the organic anion transporter family. The encoded protein is a transmembrane receptor that mediates the sodium-independent uptake of numerous endogenous compounds including bilirubin, 17-beta-glucuronosyl estradiol and leukotriene C4. This protein is also involved in the removal of drug compounds such as statins, bromosulfophthalein and rifampin from the blood into the hepatocytes. Polymorphisms in the gene encoding this protein are associated with impaired transporter function. [provided by RefSeq, Mar 2009]

Database

Research Area

REFERENCE

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REVIEW

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SDS
Sodium Azide.pdf
Package List Price ($)
$ 399