GeneTex
United States (US)

Oncostatin M recombinant protein

Cat No. GTX65192

Application ELISA, Functional Assay, Apuri, Blocking
Reactivity Human
Species Human
APPLICATION

Application Note

The ED50 as determined by the dose-dependent stimulation of the proliferation of human TF-1 cells is <2 ng/ml, corresponding to a specific activity of >5 x10^5 units/mg.

Calculated MW

26.0 kDa. ( Note )
PROPERTIES

Form

Lyophilized powder

Storage

Reconstitute in water to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers and stored at 4ºC for 1 week or –20ºC for future use.

Antigen Species

Human

Expression System

E. coli

Purification


Purity was assessed by SDS-PAGE (≥98%) and by HPLC (≥98%).

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Oncostatin M., ONCM, MGC20461, OSM

Background

Oncostatin M (OSM) is an important growth regulating cytokine that affects, variably, a number of tumor and normal cells. Oncostatin M exerts inhibitory effects on the growth of A375 melanoma and other cellos, but augments the growth of normal fibroblasts, AIDs-related Kaposi sarcoma cells, and certain other cells. Recombinant Human Oncostatin M is a 26 kDa protein containing 227 amino acid residues.
Package List Price ($)
$ 259