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PABP antibody [10E10]

Cat. No. GTX26125

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 10E10

Isotype

 IgG2b

Application

 WB, ICC/IF, IP, ELISA

Reactivity

 Human, Rabbit, Chicken, Xenopus laevis
Package
50 μl ($399)
See all PABP products

APPLICATION

Application Note

Optimal dilutions should be determined experimentally by the researcher.

Calculated MW

71 kDa. ( Note )

Product Note

Human PABP. Detects a band of approximately 70 kDa. It cross reacts with xenopus, rabbit & chicken. It does not react with mouse or drosophila

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.1% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant PABP (Human) expressed from its 1.85 kbp cDNA, NcoI to SspI

Purification

Protein A

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

poly(A) binding protein cytoplasmic 1 , PAB1 , PABP , PABP1 , PABPC2 , PABPL1

Cellular Localization

Cytoplasm , Nucleus

Background

This gene encodes a poly(A) binding protein. The protein shuttles between the nucleus and cytoplasm and binds to the 3' poly(A) tail of eukaryotic messenger RNAs via RNA-recognition motifs. The binding of this protein to poly(A) promotes ribosome recruitment and translation initiation; it is also required for poly(A) shortening which is the first step in mRNA decay. The gene is part of a small gene family including three protein-coding genes and several pseudogenes.[provided by RefSeq, Aug 2010]

Database

Research Area

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399